Preventive but nontherapeutic effect of danshensu on hypoxic pulmonary hypertension
نویسندگان
چکیده
منابع مشابه
Observations on hypoxic pulmonary hypertension.
The increase in pulmonary arterial pressure that occurs when low concentrations of oxygen are inspired (von Euler and Liljestrand, 1946) is associated with a fall in pulmonary artery oxygen saturation, and results from an increase in pulmonary arteriolar resistance (Motley et al., 1947; Lewis and Gorlin, 1952). Experiments on isolated perfused lungs in cat and dog (Hall, 1953; Duke, 1954, 1957)...
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Sustained hypoxia caused by migration of native sea-level dwellers to high altitude or by chronic lung disease leads to the development of increased pulmonary vascular resistance and pulmonary hypertension, a response to hypoxia that is unique to the pulmonary circulation. In susceptible individuals at high altitude (subacute and chronic mountain sickness) and in lung disease, the resultant pul...
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Mitochondria are essential for the onset of hypoxia-induced pulmonary vasoconstriction and pulmonary vascular-remodeling, two major aspects underlying the development of pulmonary hypertension, an incurable disease. However, hypoxia induces relaxation of systemic arteries such as femoral arteries and mitochondrial heterogeneity controls the distinct responses of pulmonary versus femoral artery ...
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ژورنال
عنوان ژورنال: Journal of International Medical Research
سال: 2020
ISSN: 0300-0605,1473-2300
DOI: 10.1177/0300060520914218